This position is listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Senior Manager, Clinical Site Payments, Portfolio Management based in United States. This is a strategic finance and operations role overseeing the financial management of investigator grant payments across a global clinical trial portfolio. You will sit at the intersection of Clinical Operations, Finance, Treasury, Sourcing, and regional payment teams. The role owns portfolio-level reconciliation, accruals, forecasting, Budget vs. Actuals analysis, and financial close activities. You will build financial models and scenarios that help leaders understand cash flow, liabilities, operational changes, and portfolio risk. The position also leads payment analytics, KPI reporting, data alignment, and dashboard development to improve financial visibility. Strong governance and audit readiness are central, with responsibility for SOX controls, documentation, reconciliations, and external audit support. This opportunity is ideal for a highly analytical finance professional who thrives in a global, fast-paced pharmaceutical or biotech environment.